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By accessing or using instituteforneurologicalresearch.com you agree to be bound by the terms and conditions of the agreement which is included on this webpage (instituteforneurologicalresearch.com/legal.htm), which actually encompasses several printed pages. If you do not wish to be bound by this agreement, you may not access or use instituteforneurologicalresearch.com. The Institute for Neurological Research, a private medical group, inc. may modify this agreement at any time, without notifying you other than by the appearance of a changed agreement on the website. You agree to review this agreement each time you access this website to ensure that you are aware of its current contents. Your continued access or use of instituteforneurologicalresearch.com shall be deemed to be conclusive acceptance by you of the agreement in its modified form. Copyright ©2009, the Institute for Neurological Research® (INR®), a private medical group, inc. The off-label methods of use and administration of certain cytokine antagonists, including etanercept, for the selected clinical disorders which are discussed on this website are patented inventions of the INR®; all rights to these patented methods of treatment are retained exclusively by the INR®. The INR® conducts a private medical practice. U.S. patents 6015557, 6177077, 6419934, 6419944, 6471961, 6537549, 6982089, 7214658 and additional issued and pending U.S. and foreign patents. These patents are assigned to TACT IP LLC.


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see: Edward Tobinick MD, Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77. (download abstracts PDF)

Cohen, et. al. Randomized, double-blind, placebo-controlled, dose-response, and preclinical safety study of transforaminal epidural etanercept for the treatment of sciatica. Anesthesiology, 2009. 110(5): p. 1116-26.

Perispinal and epidural etanercept for sciatica are patented inventions of Edward Tobinick MD, including (but not limited to) U.S. patents 6419944, 6537549, and 6982089, all assigned to TACT IP, LLC.