INR 100 UCLA Medical Plaza, Suites 205-210 Los Angeles, California 90095 (310) 824-6199 Edward Tobinick MD, Medical Director
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Disclaimer: Individual results vary. Anti-TNF treatment for the indications below is off-label. Please see the Legal Disclaimer. The videos below show actual patients of the INR who have been treated for severe disc-related pain. More than one dose may be necessary for optimal effect. Some patients do not respond. Videos filmed between 2001 and 2009.
Before and After Videos: Video1 Video2 Video3 Video4 Video5 Video 6Video 7Video 8Video 9Video 10
Video 1: 2009: Rapid relief after 5 months of severe sciatic pain

Video length 5:36 minutes. Filmed in May 2009.

Summary: This video depicts an actual patient of the INR who suffered with more than five months of constant and severe sciatica and disability, and documents her response to treatment with the patented perispinal etanercept treatment at the INR.

*See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; Tobinick, E. and S. Davoodifar, Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin, 2004. 20(7): p. 1075-85; Tobinick, E.L. and S. Britschgi-Davoodifar, Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly, 2003. 133(11-12): p. 170-7. Disclaimer: Individual results vary. Anti-TNF treatment for the indications above is off-label. Please see the Legal Disclaimer. Some patients do not respond. More than one dose may be necessary for optimal effect. The video above shows an actual patient of the INR who has been treated for severe disc-related pain.
Video 2: Improvement within minutes in severe sciatica following perispinal etanercept. Video length 8:05 minutes Perispinal etanercept injection given in 2007.

See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77
Video 3: Immediate and sustained relief from severe back pain and sciatica following a single dose of perispinal etanercept. Video length 4:25 minutes. Filmed in 2009.

See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77
Video 4: 2001: Rapid relief of neck pain and cervical radiculopathy after a single dose of the INR's patented perispinal etanercept treatment. Video length 8:29 minutes Perispinal etanercept injection given in 2001, video filmed in 2001.

*The scientific details regarding this treatment, perfomed at the INR in 2001, have been peer-reviewed and were published in 2003. see Tobinick, E., Targeted etanercept for discogenic neck pain. Clinical Therapeutics 2003 Apr;25(4):1211-8. See also Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; Tobinick, E. and S. Davoodifar, Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin, 2004. 20(7): p. 1075-85; Tobinick, E.L. and S. Britschgi-Davoodifar, Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly, 2003. 133(11-12): p. 170-7. Disclaimer: Individual results vary. Anti-TNF treatment for the indications above is off-label. Please see the Legal Disclaimer. Some patients do not respond. More than one dose may be necessary for optimal effect. The video above shows an actual patient of the INR who was treated for severe disc-related pain in 2001 at the INR.

Video 5: Relief in minutes following the patented perispinal etanercept treatment at the INR after five years of pain . Video length 1:38 minutes Perispinal etanercept injection results filmed in 2009.

*Response to a single dose of perispinal etanercept after five years of pain. The pain had failed to resolve despite dozens of disc decompression sessions, which had cost a total of $8,000 at a chiropracter's office before the patient came to the INR. Perispinal etanercept is a patented treatment developed and invented at the Institute for Neurological Research®, a private medical group, inc. in Los Angeles.See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; Tobinick, E. and S. Davoodifar, Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin, 2004. 20(7): p. 1075-85; Tobinick, E.L. and S. Britschgi-Davoodifar, Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly, 2003. 133(11-12): p. 170-7. Disclaimer: Individual results vary. Anti-TNF treatment for the indications above is off-label. Please see the Legal Disclaimer. Some patients do not respond. More than one dose may be necessary for optimal effect. The video above shows an actual patient of the INR who has been treated for severe disc-related pain.

Video 6: Response to a single dose of perispinal etanercept within minutes after 2 years of constant severe pain. Video length 8:14 minutes. 2009.

See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; and Tobinick, E., Targeted etanercept for discogenic neck pain.
Clinical Therapeutics 2003 Apr;25(4):1211-8.
Video 7: Rapid relief for an orthopedic surgeon following the patented perispinal etanercept treatment at the INR.

Video length 4:18 minutes. Filmed in 2009.

See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; Tobinick, E. and S. Davoodifar, Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin, 2004. 20(7): p. 1075-85; Tobinick, E.L. and S. Britschgi-Davoodifar, Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly, 2003. 133(11-12): p. 170-7.
Video 8: Improvement within minutes in severe, disabling sciatica following a single dose of perispinal etanercept, a patented treatment invented and available at the INR.

Video length 7:44 minutes.

Video 9: Rapid relief after 25 years of back pain following the first dose of the patented perispinal etanercept treatment at the INR.

Video length 4:16 minutes. Filmed 2009.

Video 10: Radiologist discusses his pain relief following the patented perispinal etanercept treatment at the INR.

Video length 3:26 minutes.

*See Tobinick, E., Perispinal etanercept for neuroinflammatory disorders Drug Discovery Today 2009 Feb;14(3-4):168-77; Tobinick, E. and S. Davoodifar, Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin, 2004. 20(7): p. 1075-85; Tobinick, E.L. and S. Britschgi-Davoodifar, Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly, 2003. 133(11-12): p. 170-7.

Institute for Neurological Research, a private medical group, inc.
100 UCLA Medical Plaza, Suites 205-210 Los Angeles, California 90095

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